A cold that starts with a clear runny nose and then a yellow runny nose is considered to be a viral infection followed by a bacterial infection. Colds are essentially acute upper respiratory tract infections, the vast majority of which are caused by viral infections and do not require special treatment and can be cured on their own, with a course of about 5 to 7 days. Viral infection of acute upper respiratory tract infection, clinical manifestations of nasal congestion, runny nose, fever, etc., you can take a combination of cold and flu medicines such as Meimin pseudo-ma to alleviate the symptoms. Yellow runny nose is considered to be viral infection or secondary bacterial infection, after it is clear that there is bacterial infection, antibiotics can be used to treat, such as amoxicillin, cefuroxime and so on. When symptoms such as nasal congestion, runny nose and fever are severe, antipyretic and anti-inflammatory drugs such as acetaminophen and ibuprofen can be used to relieve symptoms. If the symptoms do not improve within 2-3 days after the beginning of a cold, the patient should consult a doctor for treatment under the supervision of a physician. The above medications should be used under the supervision of a physician.