Immunohistochemistry is usually not required for normal breast pathology. The purpose of doing immunohistochemistry is to make the pathological results more accurate, usually for endocrine therapy after surgery for malignant tumors as well as the examination of targeted therapy, to determine the origin of intraductal papillomas, as well as to help in the later stage of the judgment, normal breast pathology belongs to the benign generally do not need to do immunohistochemistry. Should listen to the doctor’s advice, if necessary, need to do immunohistochemistry, to determine the trend of the disease. Immunohistochemistry generally refers to the specific staining of tissue sections, which is a method to further diagnose the disease, and can usually determine the location of malignant tumors, clarify the source of malignant tumors, and treat them. Patients are advised to undergo the test under the guidance of a doctor.