Chest pain on pressure may be costochondritis, intercostal neuralgia, rib fracture and other diseases. Chest pain when pressed should first consider the chest wall tissue lesions, their common characteristic is that there is obvious touch or pressure pain in the lesion, the lesion includes the skin, muscles, ribs, rib cartilage, and intercostal nerves distributed in the thorax with inflammation, injury or infection. 1. Costal chondritis: it may be caused by trauma, strain, inflammation, tumor and infection, and often manifests as rib pain, chest tightness and rib cartilage pressure. 2. Intercostal neuralgia: it is caused by various reasons that the thoracic nerve roots or intercostal nerves are damaged or stimulated, thus triggering severe pain and pressure in the corresponding intercostal innervation area, and the common causes include chickenpox-herpes zoster virus infection, trauma, thoracic spine diseases, tumors and so on. 3. Rib fracture: when external violence or other reasons lead to rib fracture, the fracture place appears pain, pressure pain, swelling, deformity, etc., and the patient coughs weakly and breathes shallowly. When there is chest pain when pressed should be the first time to the hospital, clear cause of the disease after active treatment, so as not to delay the condition.