If you still have pain 20 days after minimally invasive lumbar disc herniation, it may be caused by tissue damage, incomplete removal of herniated nucleus pulposus, etc., which can be treated by medicines such as methylcobalamin and re-surgery. 1. Tissue damage: when performing minimally invasive surgery for herniated disc, due to the small field of view of the surgery, the nerves and small blood vessels next to the lesion may be injured, resulting in long-lasting postoperative pain. Generally, drugs such as methylcobalamin tablets and vitamin B12 tablets can be used to nourish the nerves. If tissue adhesion occurs, surgery may be needed to release the adhesion. 2. Incomplete surgical treatment: If the protruding nucleus pulposus is not completely removed during the minimally invasive disc herniation surgery, and the herniated disc still has nerve compression symptoms, it can lead to pain 20 days after the minimally invasive lumbar disc herniation. Non-steroidal anti-inflammatory drugs such as ibuprofen and celecoxib can be used to relieve pain, and if the symptoms cannot be relieved, a second surgical procedure may be needed. 20 days after lumbar disc herniation minimally invasive or pain, it is recommended to go to the regular hospital in time to find out the cause and timely treatment. The use of drugs need to follow the doctor’s instructions.