For patients who have undergone laparoscopic cholecystectomy for gallbladder stones, if they still experience swelling and discomfort in the posterior back and right upper abdomen one month after surgery, they should have a gastroscopy if necessary to see if they have duodenal ulcers or inflammation in the duodenal area. Patients should have a gastroscopy if necessary to see if they have duodenal ulcer or inflammation in the duodenal area, because some patients with duodenal ulcer or inflammation may also show swelling and discomfort in the right upper abdomen and back, and some patients may have soreness and discomfort in the right shoulder. If it is caused by duodenal ulcer, it is recommended that patients consider taking lansoprazole, aluminum thioglycollate gel, colloidal bismuth and other drugs for active treatment at an early stage, and the patient’s symptoms will be significantly relieved after 1-2 months of treatment. If gastroscopy indicates that the duodenum and stomach are normal, the patient is considered to be suffering from abnormal bile metabolism and bile reflux. After exclusion of intrahepatic bile duct stones, patients are advised to take ursodeoxycholic acid capsules and continue observation for about one month with active treatment.