Dialysis imbalance syndrome is most often seen in patients on their first dialysis, and these patients have high blood creatinine and urea nitrogen levels prior to dialysis. If the efficiency of dialysis is high, urea nitrogen and blood creatinine fall rapidly in the blood and are quickly removed, causing an imbalance in the osmotic pressure of the intracranial and extracellular fluids, resulting in increased intracranial pressure and cerebral edema, which usually occurs during or early after dialysis. Patients can manifest as nausea, vomiting, irritability, headache, and in severe cases, convulsions, impaired consciousness, coma, or even life-threatening. Therefore, low efficiency dialysis should be used for patients on their first dialysis, which means that the dialysis time can be shortened by slowing down the blood flow rate and using a dialyzer with a smaller area to prevent the occurrence of dialysis imbalance syndrome.