How is subclinical coronary atherosclerosis screened?

  Subclinical coronary atherosclerosis is currently a hot topic and a considerable concern in terms of heart disease prevention.  Because these patients are quite dangerous, they already have atherosclerotic lesions in their arteries, and these lesions will lead to a cardiovascular event at some point, but they are completely asymptomatic themselves.  In fact, such examples are often seen in daily life, such as a celebrity who was fine yesterday and died today. How to detect patients with subclinical atherosclerosis is something we doctors should be concerned about.  A patient with subclinical atherosclerosis (Subclinical Atherosclerosis) means that we can detect the lesion through imaging methods, but they do not have any symptoms.  Without examination, we cannot call them patients yet, because there are no symptoms and signs, and only after examination, we find that there are lesions, then we call them patients.  For patients with subclinical coronary atherosclerosis, there are two means of detection.  For population screening, we use risk factors, ask about age, gender, health status of immediate family members, whether they smoke, high blood pressure, blood lipids and blood glucose, etc. In this traditional way, we can use Framingham risk score and refer to our national guidelines to classify patients into low risk, intermediate risk and high risk.  If the patient is at high risk, then interventions should be made to enhance prevention. However, for low-risk and intermediate-risk patients, the Framingham Risk Score has the major drawback of missing the test.  So now there is a second method of detection, which is an imaging technique, but this imaging technique must be non-invasive. The more widely used now are carotid ultrasound and coronary artery calcification scans. It is worth noting that a coronary artery calcification scan is not a CT imaging of the coronary arteries, but a normal CT examination that does not require contrast to enhance it.  The CT scan allows the integration of coronary artery calcification, while the carotid ultrasound mainly looks at the thickness of the intima medial layer.  Both techniques are now seen to have a substantial improvement in the Framingham risk score. Patients at low and intermediate risk can be re-risk stratified, for example, by using the Framingham risk score to rate patients as low risk, but using the coronary artery calcification score to classify patients into three major categories, both low and intermediate risk and high risk, so these types of imaging techniques can improve the ability to risk stratify.  Carotid intima-media thickness and coronary artery calcification score are relatively easy to measure. In comparison, coronary artery calcification score is more important for determining coronary heart disease, while carotid intima-media thickness is more effective for predicting stroke, so combining these two is more effective for predicting cardiovascular disease.  If we only focus on cardiovascular events, then we can screen for risk factors in low-risk and intermediate-risk patients. If you suspect that he has a problem, you can recommend him to have a coronary CT, which is cheaper and has less radiation. If the results of both techniques are not problematic, then the patient is at low risk. If the problem is redetected, the patient can be classified as intermediate risk or high risk.