The feeling of choking after taking sertraline may be related to drug side effects, drug allergies, somatic symptoms, etc. Further therapeutic measures need to be selected according to the specific causes of the symptoms.1. Drug side effects: Sertraline is a selective 5-hydroxytryptamine reuptake inhibitor, which can play an antidepressant effect and is generally indicated for the treatment of depression, anxiety disorders and other diseases. Sertraline may produce irritation to the gastrointestinal tract, causing stomach acid reflux, nausea and other conditions, there may be a feeling of being choked. This situation can be under the guidance of a doctor, reduce the amount of drugs or change the treatment drugs, you can also choose to take sertraline after meals to reduce the stimulation of sertraline on the gastrointestinal tract; 2, drug allergy: If you are allergic to the drug components in sertraline, after eating sertraline may cause edema and congestion of the mucous membrane of the throat, resulting in a feeling of choking, and may be accompanied by red spots on the skin, itching and other phenomena It may also be accompanied by redness and itching of the skin. In this case, it is necessary to stop using sertraline and take anti-allergic drugs for treatment, such as loratadine, cetirizine hydrochloride, etc.; 3. Somatic symptoms: If symptoms such as acid reflux and nausea occur after taking sertraline, or the above-mentioned somatic symptoms occur due to depression itself, the feeling of choking may also occur. This situation requires timely communication with the doctor to change the therapeutic drugs, and timely psychological counseling to find the reasons for resisting taking the medication and causing depression, anxiety and other psychosomatic diseases with the help of the doctor, and timely treatment. In life, you should keep your mood relaxed, you can do more outdoor activities, participate in more social activities, etc.. At the same time, you can eat more light and nutritious food, and try to eat less spicy and stimulating food, greasy food, sweets, etc.