Redness and swelling of vaccine needle holes are usually localized adverse reactions to vaccines and are usually normal. However, if the symptoms are more serious, it may also be due to co-infection. Redness and swelling of the needle hole after vaccination is generally a normal reaction to vaccination, as long as the diameter of the redness and swelling of the needle eye site does not exceed 3cm, there is no local fluctuation, the epidermal temperature does not increase significantly, there is no need for special treatment, generally in the vaccine can subside within 2~3 days. However, if the diameter of the redness and swelling of the vaccination site is more than 3cm, accompanied by obvious pain, and the epidermal temperature is obviously increased with fluctuation, it is considered to be the secondary infection of the vaccination site, which is caused by not paying attention to the hygiene of the vaccination port, and the local premature exposure to water, etc., and it needs to be dealt with in time. Vaccine needle hole redness and swelling is generally normal, do not need to worry too much, 2~3 days can subside. However, if the symptoms are more serious, it is recommended to consult a doctor for examination.