Estradiol is an estrogen and low estradiol values can affect follicle development and thus conception. Estradiol is very important for IVF ovulation, it can reflect the follicle development and indirectly affect the success rate of IVF, but because it is related to the number of follicle development and has a certain degree of variability, the value of Estradiol alone cannot determine whether the eggs can be retrieved, but should be considered in combination with the number and size of the follicles. Patients should be in the best physical condition before IVF, and they should pay attention to rest. After IVF, progesterone injections and other medications are needed to regulate the treatment.