The symptoms of bowel perforation after colonoscopy should be treated with anti-infection, nutritional support and surgery. 1. Anti-infection: after doing colonoscopy with bowel perforation, there will be different degrees of infection symptoms, which is not conducive to the later recovery. Therefore, antibiotics such as ceftazidime and ceftriaxone are usually chosen for treatment. 2. Nutritional support: after colonoscopy with bowel perforation, fasting and water are needed, which may be combined with infection, so intravenous energy supplementation is needed, such as fat milk, amino acid, glucose injection and so on. 3. Surgery: Surgical treatment is preferred after perforation, either laparoscopic or open surgery can be chosen. Conservative treatment or endoscopic closure of perforation can also be considered if the perforation site is in the right half of the colon or if the perforation is small. It is recommended to standardize the treatment under the guidance of physicians.