Headache with poor appetite is considered to be due to plant nerve dysfunction, as the patient’s brain is not well rested due to frequent insomnia and dreaminess, which induces ischemia and lack of oxygen in the brain followed by headache. There may also be gastrointestinal symptoms such as poor appetite, nausea, belching, acid reflux, and other poor digestion. Headaches accompanied by lack of appetite are often clinically caused by infectious diseases, such as upper respiratory tract infections or infections of other organs of the body, and bacterial toxins that cause patients to have infectious headaches and poor appetite due to inflammatory stimuli induced by toxins. The presence of headache and lack of appetite may be related to the vegetative nerves, but it is also recommended to go to the hospital can be examined to clarify whether there is inflammation, and according to the results of the examination with the doctor for symptomatic treatment.