Tazarotene cream is not a hormonal drug. The main active ingredient is tazarotene, a topical dermatologic vitamin A acid precursor drug that has the effect of regulating epidermal cell differentiation and proliferation, reducing inflammation and other effects. This drug is converted into tazarotene acid in humans and animals through a rapid degreasing process, which allows it to bind to the retinoic acid receptor and provide a therapeutic effect. Tazarotene cream is used clinically as a topical medication for the treatment of long-standing plaque psoriasis and acne vulgaris. It should be noted that it is contraindicated in pregnant and lactating women and women with recent childbearing aspirations, and should be avoided in contact with the eyes, mouth and nasal mucosa. In conclusion, this drug is not a hormonal drug and is a derivative of retinoic acid.