Chest tightness after transplantation is not a sign of successful transplantation. After successful transplantation, the main change is that the levels of progesterone, estrogen, prolactin and HCG in the body increase, and the clinical symptoms that the patient should have are mainly breast swelling and pain, deepening and enlarging of areola, and nipple erection easily, etc. Because progesterone can lead to physiological hyperplasia of the female breasts, which causes breast swelling and pain. Because the increase of progesterone can lead to physiological hyperplasia of female breasts, thus causing breast swelling and pain; the increase of estrogen level can lead to the increase of localized pigmentation of female areola, thus leading to the deepening of the color; the tightness of chest after transplantation is considered that the patient may have emotional stress, cardiovascular disease or pulmonary disease. Need to do electrocardiogram or cardiac ultrasound, observe whether there are cardiac lesions, exclude cardiac lesions have to observe whether the patient has a cough, fever and other symptoms of infection, exclude organic lesions, consider that the patient’s emotions may be excessive tension caused by.