The disease is also known as folds or interfold eruption, which occurs in the folds of the body of obese children. Cause: It is mainly due to the skin of the folds rubbing against each other, accumulation of sweat and excessive secretions, local heat cannot be distributed to increase the local temperature, thus producing erosion. Obesity, heat, humidity and poor hygiene will contribute to the occurrence of this disease. Clinical manifestations: It often starts in the second week after birth, and the skin is flushed and congested, slightly swollen, followed by papules, blisters, vesicles and oozing in the body folds, such as the front of the neck, axillae, groin and anus, and often smells bad due to chemical changes in the accumulated fluid. Sometimes satellite papules can appear due to Candida infection; if secondary bacterial infection can have purulent discharge accompanied by burning pain. The actual skin is usually clean and dry, and after bathing, use a fine soft gauze to absorb the water stains in the folds, and pounce on the non-irritating pediatric talcum powder. 2, local erythema, swelling of the external use of boric acid talcum powder or baby prickly heat powder. 3, cream or paste. 4, secondary infection, available 0.1% Levanoxyl solution wet, dry and then apply antibiotic ointment, if the Candida infection available terbinafine cream, etc..