The high white blood cell count described by the patient generally reflects the possibility of an inflammatory reaction, which is generally a bad situation. The normal range of white blood cell count is within 4000/L-10,000/L. If a patient’s white blood cell count exceeds 10,000/L and is febrile, there are two main conditions to consider: one is whether the patient has a combination of infections, including bacterial and viral infections, and other pathogens. If the patient has elevated leukocytes and fever, blood cultures should be taken if necessary, and sensitive antibiotics should be applied according to the results of the cultures, and active anti-inflammatory or antiviral treatment should be given. The other condition is that the patient has other diseases in the blood system, which is usually associated with abnormally elevated white blood cells and prolonged fever, malaise and bleeding gums. In such cases, the patient should be further hospitalized for peripheral blood smear and, if necessary, bone marrow aspiration to check for hematologic disorders.