The itchy heart and irritable discomfort may be caused by cardiac neurosis, hyperthyroidism, insufficient coronary blood supply and other diseases. 1. cardiac neurosis: is now a common clinical symptoms of cardiovascular disease as the main manifestations of clinical syndrome, subjective feeling of complexity and variety of cardiovascular symptoms, including palpitations, precordial pain, shortness of breath, combined with obvious anxiety, depression and other symptoms, will lead to itchy heart irritable uncomfortable. 2. Hyperthyroidism: It is due to the thyroid gland synthesizing and releasing too much thyroid hormone, resulting in hypermetabolism and sympathetic excitation, causing palpitations, sweating, increased eating and stooling, and weight loss, which will lead to itchy heart and irritable discomfort. 3. Insufficient coronary artery blood supply: insufficient blood supply to the heart is easy to cause palpitations, panic and other diseases. It will appear the heart itchy heart irritable uncomfortable situation. Heart itchy heart irritable uncomfortable may also have other reasons, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, give targeted treatment or treatment.