Treatment of atrophic gastritis requires suppression of stomach acid. The cause of atrophic gastritis is unknown, with Helicobacter pylori infection being the main factor, as well as autoimmune damage, chronic illnesses in the body, radiological factors, dietary factors, genetic factors, and psychiatric factors involved. Gastritis usually leads to erosion of the gastric mucosa, resulting in heartburn and epigastric pain. Some patients may also experience nausea and acid reflux. The commonly used treatment option for atrophic gastritis is usually quadruple therapy. It includes two types of antibiotics, such as amoxicillin and clarithromycin, for anti-Helicobacter pylori infection; an acid suppressant, commonly used drugs for proton pump inhibitors, such as omeprazole; and a gastric mucosal protector, such as magnesium alumina carbonate. In addition, if there is nausea, acid reflux and other gastroduodenal reflux, can be combined with cisapride, domperidone, etc., to promote gastric power drug treatment. Atrophic gastritis should go to the hospital for examination in time, and the drugs need to be used under the guidance of the doctor.