Itchy ankles the more you scratch the more itchy, may be mosquito bites, neurodermatitis, eczema and other factors. It is recommended to pay attention to the care of the affected area, a clear diagnosis, given antihistamines, glucocorticoids, antipruritic agents, can help relieve symptoms. 1. Mosquito bites: summer weather is hot, the ankle is often exposed, mosquitoes bite on the local, resulting in the more you scratch the more itchy. You can use topical glycerine lotion, oral loratadine tablets, levocetirizine tablets, to help relieve itching. 2. Neurodermatitis: Neurodermatitis, also known as chronic lichen simplex, can cause paroxysmal intense itching. It is recommended to avoid scratching, use tacrolimus ointment externally, and inject tretinoin injection if necessary, which can inhibit the inflammatory reaction and relieve the symptoms. 3. Eczema: Eczema is related to a variety of internal and external factors, which may lead to itchy ankles and wrists, and the more you scratch, the more itchy. Treatment is mainly glucocorticoid drugs, such as dexamethasone cream external coating, can also be used with oral loratadine tablets, etc., can help relieve symptoms. Itchy ankles and wrists, the more you scratch the more itchy, consider with a variety of factors related. Do not scratch to avoid infection. It is recommended to go to the dermatology department of the hospital first, to understand the causes of local itching, and can be given medication under the guidance of the doctor.