If lung adenocarcinoma recurs more than two years after early surgery, treatment plan should be formulated according to the patient’s condition after recurrence and his/her own situation. Usually, patients with small tumor volume and no distant metastasis can be treated with secondary surgery, while patients with advanced stage or distant metastasis can be treated with chemotherapy or targeted therapy.
1. Surgery: if the tumor size of patients with lung adenocarcinoma recurrence is small and no distant metastasis has occurred, they can usually consider secondary surgery to remove the lesion and lymph nodes that may have metastasis, but it should be noted that patients with heart or respiratory system diseases are not recommended to adopt surgical treatment plan.
2. Chemotherapy: If the disease stage of patients with lung adenocarcinoma recurrence is in advanced stage or distant metastasis has occurred, chemotherapy, such as docetaxel, nedaplatin, pemetrexed and so on, will usually be considered, and the specific chemotherapy drugs and programs should follow the doctor’s instructions strictly.
3. Targeted therapy: patients with recurrent lung adenocarcinoma can also undergo targeted therapy, choosing drugs such as gefitinib, crizotinib or apatinib, etc., which can help to strengthen the therapeutic effect together with the second surgery or drug chemotherapy. It should be noted that the choice of drugs for targeted therapy should be based on patients’ genetic test results and medical advice.
Therefore, if lung adenocarcinoma recurs after early surgery, it is recommended to consult a doctor as soon as possible for assessment and judgment of the stage and symptoms of lung adenocarcinoma, and adopt appropriate treatment plan. The above drugs are for reference only, and it is recommended to use them under the guidance of doctor.