FLAIR high signal usually does not heal on its own. FLAIR high signal is the result of head magnetic resonance examination, usually suggests that the patient’s brain damage or lesions, such as cerebral vascular lesions, inflammatory demyelinating lesions and other conditions may lead to FLAIR high signal.FLAIR high signal generally can not be cured by itself, and need to be treated in time to control the disease development, but it is difficult to change the high signal of the Flair that has already appeared. Cerebrovascular lesions such as cerebral hemorrhage, cerebral infarction, etc. Cerebral hemorrhage treatment is based on the principles of quiet bed rest, adjustment of blood pressure, dehydration and lowering of cranial pressure, etc. Commonly used drugs include mannitol and furosemide. Cerebral infarction requires thrombolysis, antiplatelet coagulation, etc. Commonly used drugs include recombinant tissue-type plasminogen activator (rtPA), aspirin, etc. for drug treatment. Inflammatory demyelinating lesions such as acute disseminated encephalomyelitis can be treated with high-dose methylprednisolone in the acute stage, high-dose gammaglobulin shock therapy in severe cases, etc. Glyceryl fructose and mannitol can be used to reduce intracranial pressure if there are manifestations of intracranial hypertension. FLAIR appeared high signal, it is recommended that patients go to the hospital in a timely manner to clarify the cause of the disease, and follow the doctor’s instructions for treatment, and pay attention to correct bad habits, regular rest and relaxation.