Dampness in the scrotum at the base of the buttock grooves and thighs may be due to varicocele, drug allergies, scrotal eczema and other factors. It can be relieved by physical therapy and medication. 1. Varicose veins of the spermatic cord: a vascular disease, clinically can also cause moisture in the scrotum and other parts of the scrotum, can be treated by physical therapy such as local cold compresses. It can be treated by physical therapy such as localized cold compresses. It can also be treated by surgery such as high ligation of the spermatic vein. 2. Drug allergy: allergy caused by certain drugs such as sulfonamides can lead to scrotal and surrounding skin damage, increased exudation, resulting in localized dampness. The use of the drug should be stopped immediately, and oral antihistamine drugs such as loratadine and cetirizine can be taken. All the above drugs need to pay attention to the side effects and adverse reactions of drugs, please use the above drugs under the guidance of a doctor. 3. Scrotal eczema: the main manifestation of acute scrotal eczema is itching, and localized oozing can be obvious and cause scrotal dampness and other symptoms. It can be treated with topical glucocorticosteroids and oral antihistamines such as Benadryl. All of the above medications require attention to the side effects and adverse reactions of the medications, so please use the above medications under the guidance of your doctor. There are many other reasons that can lead to the occurrence of this symptom, you should go to the hospital in a timely manner, improve the relevant examination to clarify the cause, under the guidance of the doctor’s treatment, and comply with the doctor’s instructions to use the medication.