Chronic atrophic gastritis is a gastritis in which the gastric mucosa undergoes atrophic changes. Staying up late will have an effect on the blood flow and gastric acid secretion in the stomach, so it will aggravate the condition. Atrophic gastritis is a chronic inflammation of the stomach, can be manifested as epigastric pain, loss of appetite, diarrhea and other symptoms of indigestion, staying up all night will reduce the body’s immunity, causing neuromodulation disorders, weakening the gastric mucosal protective barrier function, resulting in gastric function is impaired, so staying up all night can exacerbate atrophic gastritis. The causes of atrophic gastritis are many, such as anxiety and depression, iron deficiency anemia, long-term diet may be caused, so the discovery of atrophic gastritis, usually avoid staying up late, eat less fried and pickled foods, maintain an optimistic mindset, and timely medical attention, follow the doctor’s instructions to actively treat, and take medication on time.