Weakly positive celiac gastritis generally refers to celiac gastritis with Helicobacter pylori infection. Celiac gastritis is an endoscopic description of a disease in which there is inflammation of the gastric mucosa leading to multiple erosions. The pathogenesis of erosive gastritis, which is categorized as chronic erosive gastritis and acute erosive gastritis, is related to exogenous irritants such as aspirin and other drugs, smoking and alcohol consumption, and endogenous factors such as severe infections. Under the action of irritating factors, the epithelium of the gastric mucosa will be damaged, destroying the gastric mucosal barrier, leading to mucosal hemorrhagic erosion and bleeding, and the lesions mostly occur in the fundus and body of the stomach. Weak positivity generally refers to a positive result in the examination of Helicobacter pylori, indicating the possible existence of Helicobacter pylori infection, which needs to be diagnosed and treated in regular hospitals. Currently, the commonly used medication program for the eradication of Helicobacter pylori is the quadruple drug therapy, which generally consists of two kinds of sensitive antibiotics + a proton pump inhibitor + bismuth potassium citrate. Generally after active treatment can effectively eliminate H. pylori.