Snoring to hold awake, most commonly seen in obstructive sleep apnea hypoventilation syndrome, belongs to a category of sleep respiratory diseases, is caused by a variety of reasons in the sleep state of repeated hypoventilation and respiratory interruptions, which can lead to sleep structural disorders. Patients with this disease are often overweight or obese, and there are anatomical narrowing of the upper respiratory tract, such as nasal obstruction caused by deviated nasal septum, enlarged nasal turbinates, nasal polyps, allergic rhinitis, or nasal tumors, etc. The upper respiratory tract can also be narrowed by loose and prolapsed soft palate, narrowed pharyngeal cavity, pharyngeal tumors, overly thick and long uvula, mandibular retraction, retroverted tongue, tongue hypertrophy, and hypertrophied adenoids in children. Some endocrine system diseases such as acromegaly, hypothyroidism, etc. are also often combined with this syndrome. At the onset, there are abnormal respiratory rhythm and ventilation during sleep, almost all patients have snoring, loud and irregular snoring, which may be accompanied by intermittent respiratory pause, accompanied by gasping, waking up and termination of snoring. It is recommended that patients should consult a doctor in time for systematic examination to make a clear diagnosis when they have snoring and wakefulness.