The percentage of anti-base hemoglobin is measured to assist in the diagnosis of disorders such as bead protein production disorder anemia, multiple myeloma, and aplastic anemia. Antibasic hemoglobin is more common in newborns and pregnant women, usually 55% to 85% in newborns, and the reference range is 1% to 3.1% in healthy adults over 2 years old. Absolute and relative increases in antibasic hemoglobin have different meanings. When there is an absolute increase in the percentage of alkali-resistant hemoglobin, it may be caused by anemia with impaired pearl protein production; the relative increase in the percentage of alkali-resistant hemoglobin may be related to leukemia, aplastic anemia, multiple myeloma, lymphoma and other diseases. When the percentage of anti-base hemoglobin is abnormal, the cause of the disease should be clarified under the guidance of a doctor, and active treatment should be carried out.