Placental aging refers to low placental function leading to low and diminished role of the placenta, the cause of which may be related to a woman’s overdue pregnancy and some comorbidities during pregnancy, such as gestational diabetes and gestational hypertension. Pregnancy beyond the normal gestation period. During normal pregnancy, the placenta has an abundant blood supply to maintain the physiological functions of the placenta, while in the case of pregnancy beyond the normal gestation period, the blood supply of the placenta gradually decreases with the prolongation of the pregnancy beyond the normal gestation period, the nutrient supply gradually decreases, and the physiological functions of the placenta decline, followed by the aging of the placenta. When women have diabetes mellitus, hypertension and other comorbidities during pregnancy, the small arteries in the myometrium and metaplasia will easily cause a series of changes such as spasm, uneven thickness and thinning of the lumen, which will lead to ischemia of the blood sinus in the intervillous space after the diameter of the tube becomes smaller, and the blood volume of the placenta will be significantly reduced, thus affecting the physiological function of the placenta and placental aging. The placenta is the channel to provide nutrition for the fetus, and the aging of the placenta will easily cause fetal hypoxia, malnutrition, developmental delay, and may even lead to fetal death.