Chronic ocular keratitis should be selected according to different causes of corresponding treatment, the causes include bacterial infection, fungal infection, viral infection, etc., which can be treated by medication. 1. Bacterial infection: common staphylococcus, Pseudomonas aeruginosa, etc., can appear eye redness, pain, photophobia, tearing and other symptoms, can use tobramycin eye drops, levofloxacin eye drops and other antibiotics to control the infection. If the inflammation cannot be controlled, subconjunctival injection of antibiotics is also available. 2. Fungal infection: chronic keratitis can also be caused by fungal infections, such as Fusarium and Aspergillus, etc. Fungal keratitis has a slow onset and a long course, and can be manifested as a foreign body sensation in the eye, eye tingling, visual impairment and other symptoms, which can be treated with antifungal drugs such as amphotericin B drops, natamycin drops, miconazole drops and other drugs. 3. Viral infections: mostly caused by herpes simplex virus type I infection, often have a history of cold or fever before the onset of the disease, and accompanied by eye pain, tearing, photophobia and other symptoms, can be used ganciclovir ophthalmic gel, aciclovir eye drops and other antiviral drugs treatment. All of the above drugs should be used as prescribed by the doctor. Patients with chronic ocular keratitis should go to the hospital in time, and standardize the treatment under the guidance of the doctor.