For third-degree atrioventricular block with a heart rate of only 40 beats, the main therapeutic measures are the use of medications to elevate the heart rate and the implantation of a temporary or permanent pacemaker. 1. Drugs to elevate the heart rate: (1) Third-degree atrioventricular block, if the heart rate is too low, it will lead to insufficient ejection of blood, ischemia and hypoxia of organs, especially the brain, which will lead to fainting and even death, and it is necessary to elevate the heart rate. (2) Commonly used drugs to elevate heart rate include atropine, which is usually chosen for intravenous injection; isoprenaline, which requires cardiac monitoring during administration; and dopamine, which can be used as preparatory therapy for pacemaker therapy. 2. Temporary or permanent pacemaker implantation: patients with low ventricular rate, recurrent syncope, convulsions and As syndrome require pacemaker therapy; electrodes are implanted into the heart’s conduction system, which control the myocardium to undergo rhythmic contractions by transmitting electrical impulses. In addition to medication and surgery, patients with third-degree AV block should also pay attention to lifestyle modifications, avoiding strenuous exercise, emotional stress, oversaturation and constipation. Meanwhile, other cardiovascular diseases are actively treated.