Usually antidepressants and antipsychotics cause impotence, such as paroxetine, risperidone and diazepam. There are many causes of impotence, such as aging, obesity, medication, psychological factors, trauma and so on. In terms of medication factors, antidepressants can cause impotence in some men, and common medications include 5-hydroxytryptamine reuptake inhibitors such as paroxetine and fluoxetine. At the same time, risperidone, diazepam and other antipsychotics can also lead to impotence in some men, mainly related to adverse drug reactions. In addition to the above drugs, hydrochlorothiazide, torasemide and other diuretics, bicalutamide, finasteride and other anti-androgen drugs can also cause impotence in some men. For drug-induced impotence, male patients can follow the doctor’s instructions to change the same drug treatment or follow the doctor’s instructions to adjust the amount of medication, they also need to maintain physical and mental pleasure, to avoid excessive tension, anxiety. It is recommended to use medication under the guidance of a doctor, not to use drugs or increase or decrease the amount of medication. Daily should be appropriate abstinence sex life, masturbation, etc., try to wear cotton, loose underwear.