Myelodysplasia is commonly seen in hematological disorders such as myelodysplastic syndromes. Swelling and waxing and whitening of the face are considered to be related to anemia, hypoproteinemia, and water and sodium retention. 1. Myelodysplastic syndrome is a hematologic disease with malignant cloning of hematopoietic stem cells, in which abnormal pathological hematopoietic cell phenomenon occurs in the bone marrow, and peripheral blood shows a decrease in blood cells of the whole lineage. The clinical picture is usually characterized by anemia, which may be accompanied by infection and/or bleeding. The face may be waxy and pale in the presence of anemia. 2. Facial edema in patients with myelodysplastic syndromes is considered to be caused by hypoproteinemia, sodium retention, etc. When this disease occurs, it may be accompanied by malnutrition, electrolyte disorders, etc., leading to facial edema. When suffering from myelodysplastic syndrome, standardized treatment should be carried out under the guidance of a doctor to alleviate the condition.