An outbreak of psoriasis after the New Crown vaccine may be related to an allergic reaction to the vaccine, but it cannot be ruled out as a result of self-inflicted factors. If the outbreak of psoriasis occurs after vaccination with the New Crown vaccine, it is mainly considered to be caused by an adverse reaction to the vaccine. Since the New Crown vaccine may cause allergic reactions in some vaccinated people, especially for the skin, the possibility of triggering the disease under the stimulation of the vaccine is also one of the main reasons. However, the vaccinee’s own factors cannot be completely ruled out, as there are many factors that may trigger psoriasis, including heredity, stress, alcohol abuse, trauma, and so on, which may lead to such a situation. Therefore, it is necessary to consult a doctor in time, fully describe their situation and follow the doctor’s instructions for symptomatic treatment.