Dry syndrome is also known as Siuglien’s syndrome, or Schegren’s syndrome. It is an autoimmune disease in which one’s own immune cells attack and destroy one’s own secretory glands, including the lacrimal and salivary glands. The disease was diagnosed by Swedish ophthalmologist Henrik Euglen (1899-1986). The disease was discovered and documented by Swedish ophthalmologist Henrik Euglen (1899-1986). Dry syndrome is a chronic inflammatory autoimmune disease characterized by decreased secretion of the lacrimal and salivary glands, resulting in dry keratoconjunctivitis and oral dryness. Dry syndrome is a global disease that predominantly affects women, with the majority of onset over the age of 40. Apart from osteoarthritis, rheumatoid arthritis is the first disease in terms of incidence, and dry syndrome is the second. This disease can exist alone or appear in other autoimmune diseases, and those who exist alone are primary dry syndrome, while those who are secondary to other autoimmune diseases such as rheumatoid arthritis, systemic scleroderma and systemic lupus erythematosus are secondary dry syndrome. The etiology is still unclear, and its pathological mechanism is mainly due to the over-response reaction of autoimmunity, causing a large number of lymphocytes and plasma cells to infiltrate the exocrine glands, resulting in the destruction of glandular cells and loss of function, and thus a series of clinical symptoms and performance. According to incomplete statistics, almost all autoimmune diseases can have secondary dry syndrome, but the most common one is rheumatoid arthritis. The diagnosis of dryness syndrome is met by abnormalities in the mucus gland biopsy. It is more common in middle and old age rheumatoid arthritis patients, and 25%-30% of rheumatoid arthritis patients will have secondary dry syndrome, from which we can see the close relationship between rheumatoid arthritis and dry syndrome. There is no clear treatment for dry syndrome, only the corresponding treatment for its complications.