Streptococcus pneumoniae is the most common causative agent of bacterial meningitis, community-acquired pneumonia, and sinusitis in children over 3 months of age. Streptococcus pneumoniae infection is mainly seen in the following diseases: 1. Pediatric Streptococcus pneumoniae pneumonia: is an acute inflammation of the lungs caused by Streptococcus pneumoniae, and is a more common bacterial pneumonia in children under 5 years of age. A few have prodromal symptoms, and the onset of the disease is more acute, and may begin with brief mild symptoms of upper respiratory tract infection, followed by chills and sudden onset of high fever. Chest pain, loss of appetite, fatigue and restlessness or drowsiness, dry cough, shortness of breath exhalation moaning, nasal flapping, supraclavicular, intercostal and subcostal arch depression, etc. For pediatric Streptococcus pneumoniae, most of them have a sudden drop in temperature on day 5-10 of the course of the disease, which can drop 4-5°C within 24h. Early application of antibiotic therapy can reduce the fever within 1 to 2 days and the pulmonary signs disappear in about 1 week. Antibiotic treatment should be continued for 1 to 2 weeks, or 3 to 5 days after complete fever reduction. 2. Bacterial meningitis: It is a serious infectious disease of the central nervous system. Patients may show signs of meningeal irritation such as fever, headache, vomiting, neck tonicity, etc. In severe cases, delirium, coma, respiratory or circulatory failure may occur. For meningitis caused by Streptococcus pneumoniae, the course of antibiotics is 10-14 days. After the symptoms subside, the blood picture and lumbar puncture need to be rechecked, and if necessary, CT and MRI are done to review the brain images. Pay attention to the daily care of the baby, light and easy to digest diet.