Small blisters on the feet may be caused by herpes sweat, blistering tinea pedis, acute eczema and other diseases, need to take medication for the cause of the disease. 1. Sweat herpes: common symptoms include itching, blisters, tingling and so on. According to the severity of the symptoms can be prescribed by the application of cetirizine, loratadine and other antihistamines, as well as prednisone, tretinoin urea ointment and other glucocorticosteroid drugs, as well as tacrolimus ointment, pimecrolimus ointment, such as calcium-modulated phosphatase inhibitors. 2. Blister-type tinea pedis: the typical symptom is the presence of itchy blisters on the feet. It is necessary to follow the doctor’s advice to use topical clotrimazole, econazole, Butenafine and other antifungal drugs, or follow the doctor’s advice to take itraconazole, terbinafine and other antifungal drugs orally. 3. Acute eczema: the patient’s feet will appear itchy, corn-sized blisters, and the base is red. Glucocorticosteroids such as hydrocortisone and dexamethasone should be used as prescribed by the doctor. In severe cases, immunosuppressants such as cyclosporine and methotrexate need to be prescribed. The causes of blisters on the feet are many, patients need to go to the hospital, with the doctor to actively treat the original disease.