Chen, male, 52 years old, came to the clinic in September 2013, reported sudden onset of edema, Western medicine diagnosed as nephrotic syndrome, after hospitalization with poor results, the current stage of nasal congestion, lumbar sleepiness and leg weakness, forgetfulness, weakness, check his face, lower extremities below the knee edema obvious, both hands pulse sunken, tongue light coating smooth, concluded that edema, spleen and kidney double deficiency, prescription: Cang Er Zi, Xin Yi Hua, Angelica dahurica, Hsiang Hsiang, Atractylodes, Qiang Wu, Dou Wu, Angelica, Sheng Di, Shan Yao, Zexie, Poria, Dan Pi, mother of pearl, six doses, the previous prescription with additional reduction. The disease was relieved with six doses, and the symptoms disappeared with the addition and reduction of the previous formula for more than six months. Li, male, 56 years old, came to the clinic in March 2014, reported that he had chronic nephritis, fear of cold, edema is sometimes good and bad, this edema for more than a month taking Western medicine (dexamethasone tablets 12), the effect is not good, referred to the clinic, check his face and lower limbs below the knee edema, sunken pulse on both hands, ulnar pulse floating, yellow urine, light tongue, slippery coating, heavy nasal voice, concluded that the spleen and kidney deficiency, prescription: zedoary, yam, poria, dangdi, shamrock, niu mu cao. The edema was reduced in six doses, and the edema disappeared in two months.