In our normal life, we can often hear some friends say they are depressed, but they are relieved in three or five days without treatment, and some may have their mood relieved after sleeping at night. In these cases, as a specialist, we have to explain to them clearly, which is the normal depression reaction? What are the presenting signs of depression? So what is the difference between normal depression and depression? 1, normal depressive reactions often have a reason, such as the accidental death or injury of relatives, love and marriage discord, children’s education problems, property loss, etc., while depression has no reason; 2, normal depressive reactions are mild, and generally do not affect their lives, work and study, etc., while the degree of depression is heavy, the depressive experience is more obvious, seriously affecting their lives, work and study, and serious cases The onset time is different, normal depressive reactions can generally be relieved within a few days, usually no more than two weeks, while the course of depression is at least two weeks, or even longer; 4, depression has a tendency to recurrent episodes, and each episode is basically the same; 5, depression has obvious changes in biological rhythms, with the regular changes of heavy day and light night. 6, depression has obvious changes in physiological functions, such as loss of appetite, weight loss in some cases and slight increase in others, and loss of sexual desire.