Cough is one of the most common respiratory symptoms of childhood, and almost every child has experienced a cough of varying severity as they grow up. Some babies cough after they fall asleep at night. Frequent coughing affects children’s sleep, so it is important to identify the cause and prescribe the right medicine to cure the cough. Coughing is one of the most common symptoms of respiratory diseases in children. Under normal circumstances, coughing is a protective physiological phenomenon in babies, a defensive reflex of the body to expel respiratory secretions or foreign bodies. After sleep, the vagus nerve is excited and phlegm is stimulated, so the cough will be obvious at night. Infections such as post-cold, bronchitis and pneumonia can all have a mild or severe cough at night, which will heal successfully with treatment. Recurrent nocturnal cough does not exclude cough variant asthma and gastroesophageal reflux. Cough variant asthma is the most common cause of chronic cough, where cough is the only symptom, more pronounced at night, and antibiotic and cough suppressant treatment is ineffective and anti-asthmatic medication is effective. Most coughs caused by GERD are paroxysmal, occurring mostly at night with a violent cough. Older children may complain of epigastric or glabellar discomfort, burning sensation behind the sternum, and chest pain and sore throat. Severe gastroesophageal reflux can also lead to delayed growth and development in children. Cough suppression alone is ineffective and should be avoided before bedtime. Sleeping in a head-high, foot-low position can be supplemented with treatment with gastric mucosal protectants or Loxacol. So when your child coughs at night, help your child find the cause in time and treat the cause of the cough such as infection, allergy, airway spasm, and environmental irritation. Pay attention to strengthening your child’s physical fitness, taking appropriate outdoor exercise, eating a balanced diet, avoiding allergens in children with allergic cough, and going to less crowded public places during the disease epidemic season.