Endometrial cancer is also known as cancer of the body of the uterus. As one of the three common tumors of female reproductive tract, the incidence of endometrial cancer is on the rise and has become an “epidemic” especially among obese women. Many patients with endometrial cancer are combined with obesity, hypertension or diabetes, so be careful if your body is getting fatter and fatter! So, how can we know we have endometrial cancer? What are the detection methods? 1.B ultrasound examination B ultrasound examination can understand the size of uterus, thickness of endometrium, whether there are echogenic unevenness or redundant organisms in uterine cavity, whether there is myometrial infiltration and its degree, etc. Its diagnostic rate is over 80%. Since there are many obese patients with endometrial cancer, transvaginal ultrasound is more advantageous than transabdominal ultrasound. Because ultrasound is convenient and non-invasive, it has become the most routine test for diagnosing endometrial cancer and is also a preliminary screening method. 2.Segmental scraping Currently, it is the most common and valuable method to confirm endometrial cancer diagnosis. It can not only clarify whether it is cancer or not, whether endometrial cancer involves the cervical canal, but also distinguish endometrial cancer from cervical adenocarcinoma, so as to guide clinical treatment. For patients with heavy vaginal bleeding or continuous bleeding during perimenopause, segmental scraping can also help to stop the bleeding. The specimens from segmental scraping should be labeled and sent for pathological examination in order to confirm or exclude endometrial cancer. Hysteroscopy can directly observe the presence of cancerous lesions in uterine cavity and cervical canal, the location, size and extent of cancerous lesions, and whether the cervical canal is involved; biopsy of suspicious lesions under direct vision can help to detect smaller or earlier lesions and reduce the rate of missing endometrial cancer, and the accuracy rate of biopsy under direct vision of hysteroscopy is close to 100%. Both hysteroscopy and segmental scraping have the potential for complications such as bleeding, infection, uterine perforation, cervical laceration, and abortion syndrome, and hysteroscopy also has the risk of water poisoning. It is controversial whether hysteroscopy can lead to the spread of endometrial cancer, but most studies now believe that hysteroscopy will not affect the prognosis of endometrial cancer. 4.Cytological examination Endometrial specimens can be obtained by hysteric brush and hysteric suction smear to diagnose endometrial cancer, but its positive rate is low and is not recommended for routine application. 5.Magnetic resonance imaging Magnetic resonance imaging can show the size and scope of endometrial cancer lesions, muscle layer infiltration and metastasis of pelvic and para-aortic lymph nodes more clearly, so as to estimate the tumor stage more accurately; the resolution of CT for soft tissue is slightly lower than that of magnetic resonance imaging, therefore, in hospitals with conditions, more people apply magnetic resonance imaging for preoperative evaluation. 6.Tumor marker CA125 is generally not elevated in patients with early endometrial cancer, but it can be significantly elevated in patients with extra-uterine metastasis, and can be used as a tumor marker to detect the progress of disease and treatment effect.