There are many pathologic factors that lead to nose blockage, including rhinitis sinusitis, abnormal nasal structure, nasal mass, nasopharyngeal diseases, etc. 1. Rhinitis sinusitis: Inflammatory disease of the nasal mucosa or sinus mucosa due to bacterial, viral and other pathogenic infections, the mucosa is congested, edematous, and capillary dilatation under the attack of pathogens, resulting in hypertrophy of the turbinate and blockage of the nose. 2. Nasal structure abnormalities: such as nasal septum deviation and other diseases, due to congenital or secondary causes of nasal septum deviation, to one side or both sides of the deviation or local protrusion, to one side of the deviation leads to one side of the nasal cavity narrowing, the other side of the turbinate due to compensatory hyperplasia also leads to the gradual narrowing of the nasal cavity; if the S-type deviation is bilateral nasal congestion, causing the nose to keep clogging. 3. Nasal swelling: including nasal polyps, nasal benign and malignant tumors, etc., due to the abnormal proliferation of nasal mucosa or swelling blocking the nasal cavity, resulting in poor breathing. 4. Nasopharyngeal diseases: adenoid hypertrophy, nasopharyngeal cancer and other disorders, blocking the posterior nostril, causing the nose to be blocked. There are many pathologic factors that lead to nose blockage, and it is recommended to consult a doctor in time to avoid delaying the condition.