Rough skin with goose bumps on the legs is usually considered to be perifollicular keratosis, a chronic follicular keratinizing skin disease; this disease has a genetic predisposition, and may also be associated with vitamin deficiencies, metabolic disorders, endocrine factors, and so on. The formation of perifollicular keratosis comes from the accumulation of keratin; when the skin is hyperkeratotic, the accumulation of keratin blocks the hair follicles, causing perifollicular papules.
1. Genetic factors: 50% to 70% of patients with keratosis pilaris have a genetic predisposition, which manifests as autosomal dominant inheritance.
2. Vitamin deficiency, metabolic disorders: vitamin A, vitamin B12, vitamin C deficiency, metabolic disorders, etc. can affect the skin keratinization metabolism, which is indirectly related to perifollicular keratosis.
3. Endocrine factors: long-term use of glucocorticoid therapy or hypothyroidism patients, can appear perifollicular keratosis injury or aggravate the condition, suggesting that endocrine factors may be closely related to this disease.
It is recommended that patients with leg skin roughness and goose bumps go to a regular hospital, according to the degree of the disease, follow the doctor’s instructions to receive treatment, do not blindly deal with.