Blood in the stool is the most common early symptom of internal hemorrhoids, so people always treat blood in the stool as an attack of hemorrhoids. Because of this misunderstanding, many people tend to use some suppositories for hemorrhoids on their own when they have blood in their stool, and their symptoms can mostly improve. However, for middle-aged and elderly people, blood in stool may be a danger signal of rectal cancer, which must be alerted enough. The incidence of rectal cancer has been increasing year by year in recent years, but the early symptoms of rectal cancer are not obvious and are most easily ignored by patients and even misdiagnosed by doctors. Hemorrhoids manifest as bleeding in the anus after defecation, with bright red blood, not mixed with stool or with blood on the outside of stool, followed by dripping blood, or even jet-like bleeding, and the bleeding stops on its own after stool. Internal hemorrhoid bleeding is generally intermittent, and dry stool, fatigue, alcohol consumption, and excessive consumption of irritating food are often triggers for bleeding. In a few patients, severe anemia can occur due to long-term repeated hemorrhoid bleeding. However, blood in stool of rectal cancer is manifested as dark red blood, usually mixed with stool, with blood and mucus in stool. Of course, it is best to go to the hospital immediately for examination when blood in stool occurs, and the doctor can make a preliminary judgment by simply performing a rectal finger examination, which is an essential examination step for the diagnosis of rectal cancer. About 80% of rectal cancer patients can be detected by natural rectal finger examination at the time of consultation, and hard, bumpy masses can be palpated, and in advanced stages, narrowing of the intestinal cavity, fixed masses and fecal-containing dirty pus and blood can be seen in the finger sleeve. It is also important to emphasize that hemorrhoids can occur in the stool, but blood in the stool is not always caused by hemorrhoids. People generally believe that blood in the stool is caused by hemorrhoids, but this is not true. Blood in the stool usually occurs during defecation, dripping or jet-like bleeding during and after the stool, and the blood does not mix with the stool. Hemorrhoids are relatively easy to diagnose, but it must be noted that anorectal diseases with symptoms of blood in stool such as rectal adenoma and rectal cancer are often misdiagnosed clinically as internal hemorrhoids. Therefore, it is recommended that patients with blood in the stool must go to anorectal specialist clinics for examination as soon as possible. Even a small rectal examination may determine the type of disease, especially excluding malignant diseases, or else the time to diagnose and treat the disease will be missed.