The inability to hold in urine may be due to the presence of stress incontinence, and may also be the result of acute urinary tract infection disease, overactive bladder syndrome, prostate enlargement, neurogenic bladder, and other factors. 1. Stress incontinence: It may be related to factors such as multiple births and lack of estrogen levels. When patients perform actions that increase abdominal pressure, such as violent coughing and sneezing, they are prone to urinary leakage. 2. Acute urinary tract infection: for example, acute cystitis or acute urethritis, which may be related to poor hygiene, can be acute, when the infection is more serious, it is easy to cause urge urinary incontinence, it will lead to the urine can not be held, but also accompanied by pain in urination, frequent urination, urinary urgency and other symptoms. 3. Overactive bladder syndrome: it may be related to low estrogen level, excessive obesity and other factors, which will lead to abnormal bladder function, frequent contractions, and when it is serious, it is easy to leakage of urine, which may be accompanied by urinary urgency, frequent urination and other symptoms. 4. Prostatic hyperplasia: mainly in the elderly male group, after the gradual increase of the prostate gland, the posterior urethra caused by the pressure, so that the bladder urine gradually increased, may cause overflow incontinence, can be manifested as urinary incontinence, accompanied by frequent nocturia, urinary difficulties and other symptoms. 5. Neurogenic bladder: it may be related to hydrocephalus, craniocerebral tumors and other factors, which may lead to damage to the relevant nerves innervating the bladder, causing bladder dysfunction, which will cause urinary incontinence. There are many reasons for the phenomenon of incontinence of urine, and it is recommended that patients seek medical examination and treatment as soon as possible to avoid causing other complications.