The course of medication for LA-B grade reflux esophagitis is usually 4-8 weeks, and gastroscopy is repeated after 8 weeks to determine the healing of the esophageal mucosa in order to decide whether to discontinue the medication or to continue taking it. Grade LA-B reflux esophagitis is an endoscopic grading of the severity of reflux esophagitis, and grade B is moderate esophagitis, i.e., endoscopic observation of mucosal damage of 0.5 cm or more. The treatment is mainly based on acid suppression and promotion of gastric motility. Acid-suppressing treatment mainly chooses proton pump inhibitors, commonly used drugs are pantoprazole, esomeprazole, rabeprazole and so on. At the same time with the administration of gastric stimulating drugs, such as Itopride, Mosapride, Domperidone, etc., in order to promote the peristalsis of the esophagus and stomach and reduce reflux. The treatment time should reach at least 8 weeks before the esophageal mucosa can be repaired. In addition, after 8 weeks of medication, repeat gastroscopy again to determine the healing of the esophageal mucosa, in order to decide whether to discontinue or continue the medication next. The above medications are contraindicated in case of allergy and should be taken in accordance with medical advice. If the patient is diagnosed with reflux esophagitis, it is recommended to go to a regular hospital in a timely manner, to clarify the cause of the disease, and then carry out targeted treatment under the guidance of the doctor, in order to reduce the adverse effects of the disease.