Enlarged atria can be seen in coronary artery disease, valvular disease, and dilated cardiomyopathy. When these diseases develop to a serious stage can be life-threatening. 1. Coronary heart disease: ischemic cardiomyopathy in coronary heart disease due to long-term chronic ischemia leading to dirty remodeling, the heart is obviously enlarged, including left atrial enlargement. When myocardial ischemia to a certain extent, causing large myocardial infarction is life-threatening. 2. Valve disease: mainly including mitral stenosis or closure insufficiency, aortic stenosis or closure insufficiency, multi-valve disease, etc., when the valve lesions caused by severe symptoms or hemodynamic disorders, such as timely surgical treatment at any time will be life-threatening. 3. Dilated cardiomyopathy: myocardial lesions caused by the whole heart enlargement of the disease, if not actively treated or serious complications can be life-threatening. If you find that your heart is enlarged, you need to go to the hospital to find out the cause of the disease and get treatment according to the doctor’s instruction.