Acne is currently the main application of oral drugs are the following categories: 1, anti-sebum secretion drugs, the most common of which is spironolactone, which is also known as Amphotericin, and some female birth control pills, oral also have an effect, or cimetidine, ranitidine, etc.; 2, antibiotics are most commonly minocycline, doxycycline, clindamycin, etc.; 3, corticosteroids are more effective for severe nodular and cystic acne; 4, isotretinoin. 4, isotretinoin the most common isotretinoin pills; 5, aminophenazone is usually applied in combination with antibiotics, the course of treatment is about 3 months; 6, zinc sulfate or zinc glycyrrhiza; 7, proprietary Chinese medicine and traditional Chinese medicine, more representative of the Danshinone, Er Ding granules, etc.