The diagnosis is mainly based on the medical history, and the typical clinical manifestations are fatigue and weakness after continuous activity of the involved skeletal muscles, with obvious temporal and degree fluctuations. The affected muscle groups can be divided into extraocular muscles, facial muscles, pharyngeal muscles, cervical muscles, trunk muscles and limb muscles, etc., which can be relieved by rest or cholinergic inhibitors, and without other signs of the nervous system. In addition, one of the following tests can be performed to confirm the diagnosis: 1. Positive fatigue test: the symptoms of the affected muscle groups are significantly aggravated after continuous exercise, which is the phenomenon of muscle fatigue. In adult patients with MG, quantitative fatigue tests are emphasized and specific assessment scales are available, but in children with MG, the onset is more common in young children, and compliance with the tests is poor, and there is a lack of age-specific quantitative fatigue test scales for children; 2. The detection of acetylcholine receptor antibodies (AChRAb) is an important reference for the diagnosis of MG, if positive, it helps to diagnose, if negative, it cannot exclude the possibility of MG. 5. imaging tests: CT or MRI of the chest can help the diagnosis of thymoma. Bromipyridamole – Treatment 1. Some cases may resolve spontaneously months or years after onset; 2. Some childhood cases may persist into adulthood; 3. Although a few oculomotor forms may resolve spontaneously without treatment, most cases require treatment with immunosuppressive drugs; 4. Early treatment may reduce the possibility of progression to systemic MG; 5. Most childhood cases are clinically cured with 5. Most pediatric cases can be clinically cured with immunosuppressive therapy. Immunosuppressive drugs, including exposure hormones, have certain side effects in the near and long term in growing children; therefore, for children with first-onset MG, treatment with bromipyridamole should be preferred, especially for the simple oculomotor type, pending the arrival of natural remission. Only in case of poor results, multiple relapses, or conversion to the systemic type, the addition or change to hormones may be considered. Glucocorticoid therapy is certainly effective, while the medication should be adhered to for at least 1 year. When hormone therapy is ineffective, especially in children with MG crisis, immunoglobulin shock, plasma exchange or other immunosuppressive therapy may be used. Relapse – Prognosis The level of relapse is not related to the type of MG and the type of drug chosen, but is closely related to the duration of drug use, age and duration of disease, i.e. the shorter the duration of drug use, the older the age and the longer the duration of disease, the more likely relapse. Premature discontinuation of medication, irregular use of medication and infection are the main causes of MG relapse. MG in children is a chronic disease that requires long-term regular treatment, active prevention of infection, and reduction of relapse is the key to obtaining long-term remission. After more than one year of regular treatment, most of them have satisfactory results, and more than half of the children have achieved long-term remission, and the long-term prognosis is significantly higher than the natural remission rate.