Whether pulmonary hypertension can be vaccinated or not needs to be evaluated based on various aspects such as the patient’s status and physical condition. Pulmonary arterial hypertension will be manifested as physical fatigue, dyspnea, etc. If the situation is serious, lung infection may occur, etc. Pulmonary arterial hypertension usually occurs due to chronic obstructive pulmonary disease induced by the need to actively carry out treatment to alleviate pulmonary arterial hypertension and improve the clinical symptoms, the body can be injected with the vaccine after passing the physical review. Because patients with pulmonary hypertension are at high risk and have poor cardiac function, the injection of the new coronary vaccine may lead to deterioration of pulmonary hypertension and adverse events, which may be life-threatening. Therefore, whether or not the vaccine can be injected requires a professional doctor to evaluate the patient’s function, and if it is at a low risk, with a low incidence of adverse events, the vaccine can be injected. If a patient with pulmonary hypertension needs vaccination, it is recommended to go to the hospital in time for examination and consultation, and choose whether or not to have vaccination under the guidance of a professional doctor.