The skull is one of the hard bones in the human body. It is an important protective barrier for the brain tissue and the head and facial organs, maintaining the normal operating environment in the skull, so it plays a vital role in the life operation of the human body. If the cranial bone is damaged, it will have a negative impact on life and health, so it needs to undergo cranial bone repair surgery in time. Cranial repair surgery has been developed for thousands of years in the history of human development. In today’s modern medical context, cranial repair surgery has become a routine procedure in neurosurgery and the technique is quite mature. Cranial repair surgery usually takes place about three months after the injury. The surgery requires general anesthesia, incision of the scalp, blunt separation of the periosteum, separation of the deep fascia from the dura, complete hemostasis of the operative field, complete exposure of the bone window, taking the preoperative 3D shaped repair plate, adjusting the repositioning and fixation according to the shape of the patient’s skull defect, suspension of the dura, hemostasis of the operative cavity again, and good fixation of the temporalis muscle over the cranial repair system to achieve physiological anatomical repositioning. It is worth noting that unlike the titanium alloy material used in traditional cranial repair surgery, our team performs cranial repair surgery using a new type of polyether ether ketone, commonly known as PEEK. This PEEK material has various properties that are very close to those of autologous cranial bone, with excellent elasticity, stability, thermal insulation, hardness, etc. Moreover, it can be precisely shaped in three dimensions according to the structure of the patient’s skull, highly restoring the anatomical structure of the skull, which is highly appreciated.