The best time to take folic acid in preparation for pregnancy is usually 3 months before conception, and it is usually recommended to take it about 1-2 hours after breakfast. Folic acid is a water-soluble vitamin and is usually most effective when taken on an empty stomach. However, since folic acid may stimulate the gastrointestinal tract when taken on an empty stomach, leading to nausea, vomiting and other symptoms, it is recommended that it be taken 1-2 hours after a meal; at the same time, it is recommended that it be taken in the morning, since the morning is the time when the gastrointestinal function is most active, which is favorable for the absorption of folic acid. Folic acid can prevent pregnant women from developing anemia during pregnancy and prevent fetal developmental abnormalities, so you should start taking it before you get pregnant. Since the preparation time for pregnancy is usually around 3 months, the time to take folic acid is also usually 3 months before pregnancy. Folic acid may cause allergies and other side effect symptoms, and is contraindicated in patients with nausea anemia and suspected vitamin B12 deficiency. At the same time, if you need to use drugs should be used under the guidance of a doctor, do not blindly use drugs.